Fasalka daawada 209216-23-9 Entecavir Monohydrate ee Daaweynta Cagaarshowga B ee daba-dheeraada
| Alaabtamagac | Entecavir monohydrate |
| La mid ah | 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3- (hydroxymethyl) -2-methylenecyclopentyl]-6H-purin-6-hal monohydrate |
| CAS Maya. | 209216-23-9 |
| Muuqashada | Caddaan ilaa budo caddaan ah |
| Qaanuunka molecular | C12H15N5O3.H2O |
| Miisaanka Molecular | 295.30 |
| Isticmaalka | Darajada daawada ama ujeedada cilmi baarista |
| Baakad | Sida ku cad codsigaaga |
| Kaydinta | Ku kaydi weel cidhiidhi ah oo iftiin u adkaysta meel qabow |
| Entecavir monohydrate Cas: 209216-23-9 | ||
| Walxaha | Heerka | Natiijooyinka |
| Muuqashada | Caddaan ilaa budo caddaan ah | U hogaansama |
| Wareegga indhaha | +24.0°—+28.0°(DMF:MeOH=1:1 c=1%) | +27.0° |
| Aqoonsiga | J: By IR, Si loo waafajiyo heerka shaqada | U hogaansama |
| B: Markay tahay HPLC, wakhtiga haynta waa inuu la mid yahay heerka shaqada | U hogaansama | |
| Biyo | 5.8% - 6.5% | 6.1% |
| Isomer | Hal ≤0.1% | 0.02% |
| Wadarta ≤0.5% | 0.02% | |
| Walxaha laxidhiidha | Midka wasakhda ah ≤0.1% | 0.05% |
| Wadarta wasakhda ≤0.3% | 0.07% | |
| Hadhaaga dabka | ≤0.1% | 0.04% |
| Biraha culus | £10ppm | U hogaansama |
| Haraaga dareerayaasha | Waa inay la mid noqotaa heerka | U hogaansama |
| Qiimayn | ≥99.8% | 99.9% |
| Gabagabo:U hogaansama heerarka gudaha. | ||
Macluumaadka Shirkadda
√ Waayo-aragnimada buuxda ee lakabka maamulka ee warshadda iyo farsamayaqaannada raacsan; √ Tayada had iyo jeer waa tixgelinteena ugu sareysa, nidaamka QC adag; √ 11 sano oo khibrad u leh kooxda iibka dhoofinta; √ shaybaadhka R&D ee madaxa banaan; √ Laba aqoon-is-weydaarsiyo GMP-dheer oo saxeexan; √ Khayraadka hodanka ah ee warshado badan oo shaqo la'aan ah oo loogu talagalay mashruuc la habeeyey; √ Kooxda shaqada oo hufnaan sare leh oo leh waddo joogto ah.
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