USP 175865-59-5 Valganciclovir hydrochloride ee ka hortagga fayraska
| Alaabtamagac | Valganciclovir hydrochloride |
| La mid ah | L-Valine,2-[(2-aMino-1,6-dihydro-6-oxo-9H-purin-9-yl)Methoxy]-3-hydroxypropylester,hydrochloride(1:1);2-[(2-) amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methoxy]-3-hydroxypropyl(2S)-2-amino-3-methylbutanoatehydChemicalbookrochloridehydrate;L-Valine,2-[(2-amino-) 1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy] -3-hydroxypropylester, monohydrochloridehydrate |
| CAS Maya. | 175865-59-5 |
| Muuqashada | Budada crystalline cad ama ka baxsan |
| Qaanuunka molecular | C14H22N6O5.HCl |
| Miisaanka Molecular | 390.83 |
| Isticmaalka | Darajada daawada ama ujeedada cilmi baarista |
| Baakad | Sida ku cad codsigaaga |
| Kaydinta | Ku kaydi weel cidhiidhi ah oo iftiin u adkaysta meel qabow |
| Valganciclovir hydrochloride Cas:175865-59-5 | ||
| Walxaha | Heerka | Natiijooyinka |
| Muuqashada | Budada crystalline cad ama ka baxsan | budo cad |
| Aqoonsiga | Nuugista Infrared: Waxay la mid tahay heerka tixraacaNuugista Ultraviolet: Waxay la mid tahay heerka tixraacaXalka biyaha (1 20kiiba) ayaa buuxinaya shuruudaha shaybaarada Chloride | U hogaansama U hogaansama
U hogaansama |
| khamriga isopropyl | ≤1.0% | 0.13% |
| Biyo | ≤8.0% | 4.5% |
| Biraha culus | ≤20pm | U hogaansama |
| Pd | ≤10pm | 10pm |
| Hadhaaga shidan | ≤0.1% | 0.02% |
| wasakhda la xidhiidha | Valganciclovir: /Ganciclovir: ≤1.5%Guanin: ≤1.5% Methoxymethylguanine: ≤0.3% isovalganciclovir: ≤0.5% Monoacetoxyganciclovir: ≤0.15% Bis-valine bari ee ganciclovir: ≤0.1% Homologue of valganciclovir: ≤0.25% Imp H: ≤0.1% Imp I: ≤0.1% Ganciclovir monopropionate: ≤0.15% Valganciclovir dimer (stereoisomer A): ≤0.1% Valganciclovir dimer (stereoisomer B): ≤0.1% Valganciclovir dimer (stereoisomer C): ≤0.1% Mid kale oo la aqoonsaday: ≤0.1% Wadarta wasakhda kale ee la aqoonsaday: ≤0.1% Ganciclovir mono-N-methyl valinate (Tijaabada 2):≤0.3% Nijaasta keliya ee aan la aqoonsan (Tijaabada 1 iyo 2): ≤0.1 % Wadarta wasakhda aan la aqoonsan (Tijaabada 1 iyo 2): ≤0.25% Wadarta wasakhda (Tijaabada 1 iyo Tijaabada 2): ≤3.0 | /0.02%0.01% 0.03% 0.02% ND 0.04% 0.01% 0.01% 0.004% ND ND ND ND ugu badnaan 0.04% 0.04%
0.02% ugu badnaan 0.02% 0.13% 0.78% |
| Diastereomer saamiga | 45:55 ilaa 55:45 | 54:46 |
| Nadiifinta Enantiomeric ee valganciclovir | ≥97.0% | 99.9% |
| HPLC | 97.0% ilaa 102.0% | 98.8% |
| Gabagabo: waafaqsan USP40. | ||
Macluumaadka Shirkadda
√ Waayo-aragnimada buuxda ee lakabka maamulka ee warshadda iyo farsamayaqaannada raacsan; √ Tayada had iyo jeer waa tixgelinteena ugu sareysa, nidaamka QC adag; √ 11 sano oo khibrad u leh kooxda iibka dhoofinta; √ shaybaadhka R&D ee madaxa banaan; √ Laba aqoon-is-weydaarsiyo GMP-dheer oo saxeexan; √ Khayraadka hodanka ah ee warshado badan oo shaqo la'aan ah oo loogu talagalay mashruuc la habeeyey; √ Kooxda shaqada oo hufnaan sare leh oo leh waddo joogto ah.
